HoofXtra mix (formerly known as Laminitis Rescue)
HoofXtra mix is not a therapy or cure for laminitis. Nothing can substitute for a low sugar + starch, low-fat diet as recommended by vets like Dr Kellon VMD. It is a nutritional mineral and vitamin supplement that includes the B vitamin biotin, known to move nutrients into cells without insulin involved in other species (insulin signalling) and both pyridoxine and folic acid which may assist with nitric oxide production for blood circulation, in particular perfusion in the hooves, at levels recommended by Dr Eleanor Kellon VMD.
It was back in 2007 that Emeritus Professor Chris Pollitt at The University of Queensland and his team (Asplin KE, Sillence MN and McGowan CM) showed that elevated blood levels of insulin (hyperinsulinaemia) is a major risk factor for laminitis. Laminitis caused by elevated levels of insulin is considered the most common dietary form. Insulin controls glucose metabolism.
Elevated insulin is known to be caused by the following mechanisms:
- Insulin resistance (IR), a state where the tissues show a reduced sensitivity to insulin resulting in an overproduction of insulin.
- Gut hormones called incretins (GLP-1 and GIP) are produced in the intestine to enhance insulin release for the purpose of stabilising blood glucose levels. Abnormal high insulin has been linked to higher levels of a type of incretin (GLP-1).
To prevent laminitis caused by elevated insulin regardless of mechanism, the key is a diet low in sugar and starch as it’s these carbohydrates that trigger the release of insulin from the pancreas.
Copper: Involved in enzymes required for aerobic metabolism in rapidly dividing cells including the process that forms the sulfur components that hold keratin strands together in hair and hooves.
Zinc: Essential for interactions between proteins and a variety of enzymes that all metabolically active cells require for cell multiplication and maturation. Zinc is a key component of ‘zinc finger proteins’ in the assembly of keratin, a hoof building material. A zinc deficiency can be expressed as slow hoof growth, thin walls and weak connections and horn.
When not deficient, copper and zinc prevent the fats and oils in the protective seal on the hoof from oxidising. Oxidative damage causes over drying and weakens the connections between cells. When the hoof is weak, it is more vulnerable to attack by organisms via microscopic cracks. In cattle, deficiencies in either copper or zinc have been linked to soft feet, cracks, abscesses, thrush and laminitis.
Magnesium: The symptoms of a magnesium deficiency are the same as for excessive ionised calcium compared to magnesium. Symptoms include twitching, irritability, and hypersensitivity. Magnesium has many different jobs to do in the body and one of the most important is to control ‘excitable’ tissue activity, including the nervous system, heart, skeletal muscle and smooth muscle in the intestinal tract, uterus, urinary tract and blood vessels.
Biotin: Has a role in general metabolism and in maintaining integrity of skin, hair and hooves.
Pyridoxine: Has a role in normal general metabolism, nervous system function and vision, involved in red blood cell formation and in maintaining normal healthy skin and vision.
Folic acid: Involved in general metabolism, in blood cell production and the formation of red and white blood cells and haemoglobin.
Selenium: Selenium is an important antioxidant for protecting cell structures and cell membranes from the effects of oxygen free radicals produced during energy generation and therefore most important for tissues with high aerobic metabolism activity like the brain/nervous system, heart, skeletal muscles and rapidly growing tissues.
Acidic soils inhibit selenium uptake by plants. Alkaline soils are more likely to have adequate selenium levels though horses in work may need supplementation.
A soil test will test pH, the lower the pH number the higher the acidity, 7 is neutral and the higher the number the more alkaline the soil.
The standard feeding rate contains 1 mg selenium. If you are concerned about overdoing selenium, Dr Kellon's article may help: https://uckeleequine.wordpress.com/2014/10/09/selenium-paranoia/
This product is contraindicated for use when selenium intake from pasture is high or selenium is provided by other means (such as top dressing, vaccine, pellets or selenium drenches) if blood selenium levels at treatment are high. Users can determine selenium status by consulting their veterinarian.
HoofXtra mix is a nutritional supplement product for inclusion in horse's feed. The product has no therapeutic effect and is designed to be administered in a feed for voluntary ingestion for horses.
The standard feeding rate is 17 grams or a 1.2 metric tablespoon (slightly heaped tablespoon, best to weigh). For ponies under 300 kg, 1/2 tablespoon.
Iodised salt is recommended for the salt supplementation you add to a feed, at least 2 tablespoons per day, more in hot weather.
Horse consumption only.
3 kg - will last just under 6 months on the standard feeding rate for one horse